反应详情

To a solution of ethyl 2,4-dioxo-4-phenylbutanoate (16.0 g) in ethanol (150 mL) was added hydrazine monohydrate (4.0 mL), and the mixture was heated under reflux for 3 hr. The reaction mixture was concentrated under reduced pressure, and the residue was crystallized from diisopropyl ether to give the title compound as a pale-brown solid (yield 12.0 g, 67%).

1. temperaturethe mixture was heated
2. temperatureunder reflux for 3 hr
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. customthe residue was crystallized from diisopropyl ether