Potassium Carbonate → HCID 66825684, compound

HRID 2359978Notes

Reaction equation

HRID 2359978 reaction equation
Cl[C:2]1[N:6]([CH3:7])[N:5]=[C:4]([CH:8]([F:10])[F:9])[C:3]=1[CH:11]=[O:12].[F:13][C:14]([F:23])([F:22])[C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][CH:16]=1.C(=O)([O-])[O-:25].[K+].[K+]>>[F:9][CH:8]([F:10])[C:4]1[C:3]([C:11]([OH:12])=[O:25])=[C:2]([O:21][C:18]2[CH:17]=[CH:16][C:15]([C:14]([F:22])([F:23])[F:13])=[CH:20][CH:19]=2)[N:6]([CH3:7])[N:5]=1

Participants

4

Procedure

The title compound was prepared using 5-chloro-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carbaldehyde and 4-(trifluoromethyl)phenol in the manner similar to the method in Production Example 1 above except potassium carbonate was used instead of potassium hydroxide.

Sources & evidence

ORD record
ord-7353965e39e54b598b286cbecd1372b8
Source dataset
uspto-grants-2014_04
Patent number
US08686018B2

Reaction notes

Loading…