HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 7-amino-8-(2-methylpropyl)-6-nitroso-2,3-dihydroimidazo[1,2-a]pyrimidin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 7-AMINO-2,3-DIHYDRO-8-(2-METHYLPROPYL)IMIDAZO[1,2-a]PYRIMIDIN-5(8H)-ONE | HCID 13100554 | — |
| Reactant | Sodium Nitrite | HCID 23668193 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 7-amino-8-(2-methylpropyl)-6-nitroso-2,3-dihydroimidazo[1,2-a]pyrimidin-5-one | HCID 178448426 | — |
Reaction Steps
To a solution of 5.00 g. (0.024 mole) of the product of Procedure 30 in 15 ml. H2O and 4 ml. HOAc (0°) was added (portionwise) 1.72 g. (0.024 mole) NaNO2. The mixture was stirred at 24° for 30 min., cooled to 0° and filtered to yield 4.44 g. (72%) of a purple solid, mp 203°-205°d.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04642345 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-4a78f15917c64849b1b1e32a349ba1d8 |
| Source note | uspto-grants-1987_02 |