HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citric Acid → HCID 86658825, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Sunitinib | HCID 5329102 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 86658825 | HCID 86658825 | — |
Reaction Steps
Sunitinib (2.21 g, 5.55 mmol) suspended in methanol (75 ml), 1.07 g of citric acid was added. Mixture was stirred at room temperature for several hours, and then filtered to obtain crystalline sunitinib citrate, 3.2 g. Melting point: 166-174° C. (Form I).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686023B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-778ef29c63e241ab82928d8080f28ebb |
| Source note | uspto-grants-2014_04 |