HuagongsheHuagongshe Chemistry Print Report · For research reference only
Citric Acid → HCID 86658825, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Citric Acid | HCID 311 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Sunitinib | HCID 5329102 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 86658825 | HCID 86658825 | — |
Reaction Steps
Sunitinib (2.25 g, 5.65 mmol) and citric acid (1.09 g, 5.65 mmol) were dissolved while heating in the mixture of methanol (100 ml) and water (10 ml). The solution was left to cool to room temperature to give sunitinib citrate. Melting point: 168-173° C. (Form I).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686023B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-271aa0259be646e59081d0d20cab9e21 |
| Source note | uspto-grants-2014_04 |