4-Bromo-2,6-dichloroaniline → HCID 66997456, compound

HRID 2360422Notes

Reaction equation

HRID 2360422 reaction equation
Br[C:2]1[CH:8]=[C:7]([Cl:9])[C:5]([NH2:6])=[C:4]([Cl:10])[CH:3]=1.[Cl:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1B(O)O>>[Cl:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][C:13]=1[C:2]1[CH:8]=[C:7]([Cl:9])[C:5]([NH2:6])=[C:4]([Cl:10])[CH:3]=1

Participants

3

Reactant 2

HCID 696804-Bromo-2,6-dichloroanilineHCID 27343222-Chlorophenylboronic acid

Product 1

HCID 66997456HCID 66997456, compoundYield 69.9%

Procedure

The title compound (0.4 g) was prepared from 4-bromo-2,6-dichloroaniline (0.5 g, 2.1 mmol) and 2-chlorophenylboronic acid (0.421 g, 2.7 mmol) as a white solid. 1H-NMR (δ ppm, DMSO-d6, 400 MHz): 7.55-7.50 (m, 1H), 7.40-7.32 (m, 3H), 7.29 (s, 2H), 5.72 (s, 2H).

Sources & evidence

ORD record
ord-9a21214b289b487c880f76a26f7f6e30
Source dataset
uspto-grants-2014_04
Patent number
US08686048B2

Reaction notes

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