HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzyl Alcohol → HCID 59321323, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzyl Alcohol | HCID 244 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 1,3,5-Trifluoro-2-nitrobenzene | HCID 67567 | — |
| Reactant | Water ethylacetate | HCID 22728543 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 59321323 | HCID 59321323 | 70.2% |
Reaction Steps
Potassium carbonate (544 mg, 3.94 mmol) and benzyl alcohol (0.3 ml, 2.8 mmol) were added to a solution of 2,4,6-trifluoronitrobenzene (500 mg, 2.8 mmol) in DMF (5 ml). This mixture was stirred at RT overnight. Work up (EtOAc/H2O) afforded the title compound (521 mg) as a yellow liquid which was used in the next step without fuRTher purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08686048B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-4d11d62618d148f7ba6ad03a4ba6058d |
| Source note | uspto-grants-2014_04 |