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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360497Generated: November 3, 2026

Hydrochloric Acid → HCID 66986037, compound

https://huagongshe.com/reaction/2360497

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 76803534HCID 76803534—
SolventIsopropanolHCID 3776—
SolventDichloromethaneHCID 6344—
ProductHCID 66986037HCID 66986037—

Reaction Steps

1.59 g tert-butyl [5-tert-butyl-2-methoxy-3-({1-methyl-7-[4-(1-methyl-pyrrolidine-2-carbonyl)-piperazin-1-ylmethyl]-1H-indole-2-carbonyl}-amino)-phenyl]-carbamate are dissolved in 15 ml dichloromethane, combined with 10 ml of a 5 M solution of hydrogen chloride in isopropanol and stirred for 3 hours at ambient temperature. Then the solvents are eliminated in vacuo. The product thus obtained is further reacted directly.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686022B2
Source datasetuspto-grants-2014_04
ORD IDord-10f45afe418a485398b96817618349de
Source noteuspto-grants-2014_04