反应详情

温度

0 °C

3.43 g (5-tert-butyl-2-methoxy-3-nitro-phenyl)-methanol are dissolved in 30 ml dichloromethane, combined with 2.39 ml of triethylamine and cooled to 0° C. 1.2 g of methanesulphonic acid chloride are added dropwise and the mixture is stirred for 2 hours. Then it is diluted with dichloromethane and washed 3 times with water and once with saturated aqueous sodium chloride solution. After drying with magnesium sulphate the solvents are eliminated in vacuo and the product thus obtained is further reacted directly.

1. washwashed 3 times with water
2. dry with materialAfter drying with magnesium sulphate the solvents
3. customthe product thus obtained
4. customis further reacted directly