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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2360523Generated: November 2, 2026

3-(Morpholin-4-yl)aniline → HCID 46190508, compound

https://huagongshe.com/reaction/2360523

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-(Morpholin-4-yl)anilineHCID 847768—
ReactantMethanaminium, N-((dimethylamino)(3H-1,2,3-triazolo(4,5-b)pyridin-3-yloxy)methylene)-N-methyl-, hexafluorophosphate(1-) (1:1)HCID 9886157—
ReactantHCID 66769300HCID 66769300—
ProductHCID 46190508HCID 46190508—

Reaction Steps

1-methyl-7-[4-(1-methyl-pyrrolidine-2-carbonyl)-piperazin-1-ylmethyl]-1H-indole-2-carboxylic acid and 3-morpholin-4-yl-phenylamine are used as reactants. O-(7-Azabenzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium-hexafluorophosphate (HATU) is used instead of O-(benzotriazol-1-yl)-N,N,N′,N′-tetramethyluronium-tetrafluoroborate (TBTU).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08686022B2
Source datasetuspto-grants-2014_04
ORD IDord-4b84387755c44949a354e22b61c37645
Source noteuspto-grants-2014_04