4-Phenylthiocyclohexanone Oxime → HCID 20217891, compound

HRID 236106Notes

Reaction equation

HRID 236106 reaction equation
[C:1]1([S:7][CH:8]2[CH2:13][CH2:12][C:11](=[N:14]O)[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].C([Al+]CC(C)C)C(C)C>C(Cl)Cl>[C:1]1([S:7][CH:8]2[CH2:13][CH2:12][CH2:11][NH:14][CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 2

HCID 202178614-Phenylthiocyclohexanone OximeHCID 21225700Diisobutylaluminumhydride

Product 1

HCID 20217891HCID 20217891, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Following an analogous procedure to that of Sasatani, S. et al. described in Tetrahedron Letters, Vol. 24 (No. 43), pp 4711-4712 (1982), 4-phenylthiocyclohexanone oxime is reacted with diisobutyl aluminum hydride in methylene chloride to give the title compound.

Sources & evidence

ORD record
ord-003f739b4cc34785830a189acfed03aa
Source dataset
uspto-grants-1987_02
Patent number
US04642348

Reaction notes

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