N,N-Diethylethylenediamine → HCID 13608033, compound

HRID 236115Notes

Reaction equation

HRID 236115 reaction equation
[CH2:1]([N:3]([CH2:6][CH2:7][NH2:8])[CH2:4][CH3:5])[CH3:2].[C:9](N1C=CN=C1)(N1C=CN=C1)=[O:10].[CH3:21][N:22]([CH3:41])[CH2:23][CH2:24][O:25][C:26]1[CH:31]=[CH:30][C:29]([S:32]([CH:35]2[CH2:40][CH2:39][CH2:38][NH:37][CH2:36]2)(=[O:34])=[O:33])=[CH:28][CH:27]=1>>[CH2:1]([N:3]([CH2:4][CH3:5])[CH2:6][CH2:7][NH:8][C:9]([N:37]1[CH2:38][CH2:39][CH2:40][CH:35]([S:32]([C:29]2[CH:28]=[CH:27][C:26]([O:25][CH2:24][CH2:23][N:22]([CH3:41])[CH3:21])=[CH:31][CH:30]=2)(=[O:34])=[O:33])[CH2:36]1)=[O:10])[CH3:2]

Participants

4

Reactant 3

HCID 60993N,N-DiethylethylenediamineHCID 682631,1'-CarbonyldiimidazoleHCID 13607992HCID 13607992, compound

Product 1

HCID 13608033HCID 13608033, compoundYield 33.1%

Procedure

Following the procedure of Example 16, N,N-diethyl aminoethylamine and 1,1'-carbonyldiimidazole and N,N-dimethyl-2-[4-[(3-piperidinyl)sulfonyl]phenoxy]ethanamine were reacted to give the title compound which was crystallized from diethyl ether-hexane as white crystals in 33.1% yield, m.p. 79°-80° C.

Workup

  1. customwere reacted

Sources & evidence

ORD record
ord-9a61de55d8e34ec7992b6c46f4abb20f
Source dataset
uspto-grants-1987_02
Patent number
US04642348

Reaction notes

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