Oxalic Acid → N-[2-(Diethylamino)ethyl]-4-(phenylthio)-1-homopiperidinecarboxamide Oxalate

HRID 236118Notes

Reaction equation

HRID 236118 reaction equation
[C:1]([N:8]1[CH:12]=[CH:11][N:10]=[CH:9]1)([N:3]1[CH:7]=[CH:6]N=[CH:4]1)=[O:2].[CH2:13](NN(CC)NCC)[CH3:14].[C:22]1([S:28][CH:29]2CCCN[CH2:31][CH2:30]2)[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1.[C:36]([OH:41])(=[O:40])[C:37]([OH:39])=[O:38]>>[C:36]([OH:41])(=[O:40])[C:37]([OH:39])=[O:38].[CH2:13]([N:10]([CH2:9][CH3:36])[CH2:11][CH2:12][NH:8][C:1]([N:3]1[CH2:4][CH2:31][CH2:30][CH:29]([S:28][C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=2)[CH2:6][CH2:7]1)=[O:2])[CH3:14]

Participants

5

Reactant 4

HCID 971Oxalic AcidHCID 682631,1'-CarbonyldiimidazoleHCID 20217891HCID 20217891, compoundHCID 57254831N,N-diethylaminoethylamine

Product 1

HCID 20217850N-[2-(Diethylamino)ethyl]-4-(phenylthio)-1-homopiperidinecarboxamide Oxalate

Procedure

Following the procedure of Example 16, 1,1'-carbonyldiimidazole, N,N-diethylaminoethylamine and 4-(phenylthio)homopiperidine and oxalic acid are reacted to give the title compound.

Workup

  1. customare reacted

Sources & evidence

ORD record
ord-62ba13ec94394a0b92ee725fff4020d8
Source dataset
uspto-grants-1987_02
Patent number
US04642348

Reaction notes

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