反应详情

温度

115 °C

To a sealed tube equipped with a magnetic stir bar, containing 1,1-dimethoxy-N,N-dimethylmethanamine (50 mL) was placed 1-(3-nitrophenyl)ethanone (5 g, 30 mmol, 1.0 equiv). The reaction was allowed to stir at 115° C. for 15 h. After the reaction was complete by LCMS, the solid product was filtered and washed with ether to yield 5.3 g (80%) of DHK-7-12 as an yellow solid. MS (ESI, Pos.) m/z: 221.1 [M+H]+.

1. customTo a sealed tube equipped with a magnetic stir bar
2. filtrationthe solid product was filtered
3. washwashed with ether
4. customto yield 5.3 g (80%) of DHK-7-12 as an yellow solid