Triethylamine → HCID 68484012, compound

HRID 2361568Notes

Reaction equation

HRID 2361568 reaction equation
[CH3:1][CH:2]1[CH:7]=[C:6]([CH3:8])[CH2:5][CH2:4][C:3]1([C:12](=[O:16])[CH2:13][CH:14]=[CH2:15])[C:9]([CH3:11])=[CH2:10].C(N(CC)CC)C>C(Cl)Cl>[CH3:1][CH:2]1[CH:7]=[C:6]([CH3:8])[CH2:5][CH2:4][C:3]1([C:12](=[O:16])[CH:13]=[CH:14][CH3:15])[C:9]([CH3:11])=[CH2:10]

Participants

4

Reactant 2

HCID 8471TriethylamineHCID 68478251HCID 68478251, compound

Product 1

HCID 68484012HCID 68484012, compoundYield 80%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 1-(2,4-dimethyl-1-(prop-1-en-2-yl)cyclohex-3-enyl)but-3-en-1-one (2.5 g, 11.5 mmol) and triethylamine (2 g) in CH2Cl2 was stirred at room temperature over night. The solvent and excess of triethylamine were evaporated and the residue distilled bulb-to-bulb to yield the title compound (80%) as a slightly yellow oil.

Workup

  1. customThe solvent and excess of triethylamine were evaporated
  2. distillationthe residue distilled bulb-to-bulb

Sources & evidence

ORD record
ord-b746f8ac129b4348810e500a630b7261
Source dataset
uspto-grants-2014_04
Patent number
US08691746B2

Reaction notes

Loading…