Methyl Methanesulfonate → HCID 86649733, compound

HRID 2361861Notes

Reaction equation

HRID 2361861 reaction equation
[NH2:1][C:2]1[N:3]=[N:4][CH:5]=[CH:6][N:7]=1.[CH3:8][S:9]([O:12]C)(=[O:11])=[O:10].[CH3:14]N(C)C=O>CO>[S:9]([OH:12])(=[O:11])(=[O:10])[CH3:8].[NH2:1][C:2]1[N:3]([CH3:14])[NH:4][CH:5]=[CH:6][N:7]=1

Participants

5

Reactant 3

HCID 4156Methyl MethanesulfonateHCID 6228DimethylformamideHCID 707153-Amino-1,2,4-triazine

Product 1

HCID 86649733HCID 86649733, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

A mixture of the 3-amino-1,2,4-triazine [6] (500 mg), methyl methanesulphonate (0.5 cm3), dimethylformamide (0.5 cm3) and methanol (10 cm3) was stirred at 60° for 30 mins. and the resulting deep yellow solution allowed to stand at room temperature for 24 hrs. The deep yellow plates that were deposited were filtered off washed with acetone-ether (1:1) and dried.

Workup

  1. waitto stand at room temperature for 24 hrs
  2. filtrationThe deep yellow plates that were deposited were filtered off
  3. washwashed with acetone-ether (1:1)
  4. customdried

Sources & evidence

ORD record
ord-491dd926a7f842b898c7a7e6d5751710
Source dataset
uspto-grants-2014_04
Patent number
US08691818B2

Reaction notes

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