Ethane, 2-bromo-1,1-diethoxy- → HCID 37979251, compound

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Reaction Steps

According to the procedure described in the synthesis method of Compound IX-1, 2-bromo-1,1-diethoxyethane (41.3 ml, 270 mmol) was reacted with (R)-(+)-1-phenylethylamine (66.6 g, 550 mmol) and the obtained residue was purified by silica gel column chromatography (eluent: n-hexane:ethyl acetate=5:1 and 1:1) to obtain the title compound (46.0 g, 70%).

Provenance & Evidence