反应详情

温度

100 °C

A mixture of 5-1 (150 mg, 0.36 mmol) and 2-Bromo-1-phenyl-ethanone (110 mg, 0.54 mmol) in ethanol (2 mL) was heated to 100° C. and stirred for 45 mins under microwave radiation. The mixture was cooled to r.t. and diluted with 20 mL of DCM. The organic phase was washed with brine, dried over anhydrous Na2SO4 and concentrated. The residue was purified by prep.TLC to give 90 mg of 5-2.

1. temperatureThe mixture was cooled to r.t.
2. washThe organic phase was washed with brine
3. dry with materialdried over anhydrous Na2SO4
4. concentrationconcentrated
5. customThe residue was purified by prep.TLC