HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 86673428, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 59525761 | HCID 59525761 | — |
| Reactant | HCID 86673423 | HCID 86673423 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 86673428 | HCID 86673428 | — |
Reaction Steps
Prepared according to the same procedure as diethyl 2,5-difluorobenzylphosphonate, starting with 2-(bromomethyl)-4-chloropyrimidine. Analytical HPLC method: Phenomenex LUNA C18, 50×2 3μ, A=90% H2O/10% CH3CN, B=90% CH3CN/10% H2O, Modifier 0.1% TFA, 0.00 min=0% B, 4.0 min=100% B, 5.0 min=100% B, Flow rate=0.8 mL/min. Mass spec.: 265.1 (MH)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691821B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-9c1bcbd9f2d94edcab471e4c52f6c9be |
| Source note | uspto-grants-2014_04 |