HCID 140570811, compound → HCID 136351076, compound

HRID 2362648Notes

Reaction equation

HRID 2362648 reaction equation
[NH2:1]/[C:2](=[N:26]\[O:27][C:28]([CH:30]1[CH2:35][CH2:34][CH2:33][N:32]([C:36]([O:38][C:39]([CH3:42])([CH3:41])[CH3:40])=[O:37])[CH2:31]1)=O)/[C:3]1[NH:25][C:6]2=[N:7][CH:8]=[C:9]([Cl:24])[C:10]([C:11]3[S:15][C:14]([C:16]4([O:20][CH2:21][O:22][CH3:23])[CH2:19][CH2:18][CH2:17]4)=[N:13][CH:12]=3)=[C:5]2[CH:4]=1>C1(C)C=CC=CC=1>[Cl:24][C:9]1[C:10]([C:11]2[S:15][C:14]([C:16]3([O:20][CH2:21][O:22][CH3:23])[CH2:17][CH2:18][CH2:19]3)=[N:13][CH:12]=2)=[C:5]2[CH:4]=[C:3]([C:2]3[N:1]=[C:28]([CH:30]4[CH2:35][CH2:34][CH2:33][N:32]([C:36]([O:38][C:39]([CH3:40])([CH3:41])[CH3:42])=[O:37])[CH2:31]4)[O:27][N:26]=3)[NH:25][C:6]2=[N:7][CH:8]=1

Participants

3

Reactant 1

HCID 140570811HCID 140570811, compound

Product 1

HCID 136351076HCID 136351076, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

A solution of Example 22C (0.084 g, 0.136 mmol) in toluene (3 mL) was heated to 110° C. for 10 hours. The reaction was cooled to ambient temperature and concentrated to give the title compound, which was used without further purification. MS ESI(+) m/z 601.2 [M+H]+.

Workup

  1. concentrationconcentrated

Sources & evidence

ORD record
ord-72af7e1f0e4c4b4592bba64c89469f50
Source dataset
uspto-grants-2014_04
Patent number
US08691810B2

Reaction notes

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