Hydrazine hydrate (1:1) → HCID 70430401, compound

HRID 236274Notes

Reaction equation

HRID 236274 reaction equation
[CH3:1][C:2]1([CH2:7][C:8]2[S:12][C:11]([C:13](=O)[CH2:14][CH2:15][C:16]([OH:18])=O)=[CH:10][CH:9]=2)[N:6]=[CH:5][CH:4]=[N:3]1.O.[NH2:21][NH2:22]>O>[CH3:1][C:2]1([CH2:7][C:8]2[S:12][C:11]([C:13]3[CH2:14][CH2:15][C:16](=[O:18])[NH:21][N:22]=3)=[CH:10][CH:9]=2)[N:6]=[CH:5][CH:4]=[N:3]1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 70429268HCID 70429268, compound

Product 1

HCID 70430401HCID 70430401, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
100 °C

Procedure

A mixture of 3 g of 4-[5-(2-methyl-1-imidazolyl-methyl)-thien-2-yl]-4-oxobutyric acid, 0.54 ml of hydrazine hydrate and 50 ml water was heated for 2 hours at 100° C. After cooling the precipitated solid was filtered off, washed with water and dried.

Workup

  1. temperatureAfter cooling the precipitated solid
  2. filtrationwas filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-a17bb29b04e345a98eef6b8e5634cb74
Source dataset
uspto-grants-1987_02
Patent number
US04643998

Reaction notes

Loading…