Hydrazine hydrate (1:1) → HCID 70430400, compound

HRID 236277Notes

Reaction equation

HRID 236277 reaction equation
[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][C:7]1[CH:8]=[C:9]([C:12](=O)[CH2:13][CH2:14][C:15]([OH:17])=O)[S:10][CH:11]=1.O.[NH2:20][NH2:21]>O>[NH:1]1[CH:5]=[CH:4][N:3]=[C:2]1[CH2:6][C:7]1[CH:8]=[C:9]([C:12]2[CH2:13][CH2:14][C:15](=[O:17])[NH:20][N:21]=2)[S:10][CH:11]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 70429249HCID 70429249, compound

Product 1

HCID 70430400HCID 70430400, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
90 °C

Procedure

A mixture of 5.6 g of 4-[4-(1-imidazolylmethyl)-thien-2-yl]-4-oxobutyric acid, 1.1 g hydrazine hydrate and 50 ml water was stirred for 2 hours at 90° C. After cooling, the precipitated solid was filtered off, washed with water and dried.

Workup

  1. temperatureAfter cooling
  2. filtrationthe precipitated solid was filtered off
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-54545f0a285448a58ca58f0e5ba41c7f
Source dataset
uspto-grants-1987_02
Patent number
US04643998

Reaction notes

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