反应详情

0.765 g (11.6 mmol) of malononitrile, 1.28 g (11.6 mmol) of thiophenol and 2.48 g (11.6 mmol) of 2-[4-(2-hydroxyethoxy)benzylidene]malononitrile [preparation according to WO 03/053441, Example 6/Method 2, Step 1] are dissolved in 15 ml of ethanol, and 0.03 ml of triethylamine is added. The mixture is stirred under reflux for 2 h. After cooling, the reaction mixture is filtered and the residue is washed with ethanol and dried.

1. temperatureunder reflux for 2 h
2. temperatureAfter cooling
3. filtrationthe reaction mixture is filtered
4. washthe residue is washed with ethanol
5. customdried