反应详情

温度

50 °C

A solution of 10 mL ethanol and 2 mL sodium carbonate 2N is saturated in hydrogen sulfur. 500 mg (2 mmoles) 3-nitrocinnamaldehyde thiosemicarbazone prepared in step 2A are added. The solution is heated 10 minutes at 50° C., then 3 minutes at 75° C. The solution is cooled in a ice bath. The crystals formed are filtered, washed with ethanol. 299 mg of 3-aminocinnamaldehyde thiosemicarbazone is obtained. Yield 68%.

1. custom3 minutes
2. customat 75° C
3. temperatureThe solution is cooled in a ice bath
4. customThe crystals formed
5. filtrationare filtered
6. washwashed with ethanol