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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362874Generated: October 30, 2026

Hydrochloric Acid → HCID 66652211, compound

https://huagongshe.com/reaction/2362874

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046642HCID 58046642—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652211HCID 66652211—

Reaction Steps

To (S)-tert-butyl 3-(3-(sec-butoxycarbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.072 g, 0.14 mmol) was added 4M solution of HCl in dioxane (1.5 mL). After stirring at room temperature for an hour, the reaction mixture was concentrated in vacuo to obtain (S)-sec-butyl 3-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-2f5046494b4846bdbe3204251fcf65fd
Source noteuspto-grants-2014_04