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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362885Generated: October 30, 2026

Hydrochloric Acid → HCID 66652067, compound

https://huagongshe.com/reaction/2362885

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046775HCID 58046775—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652067HCID 66652067—

Reaction Steps

To tert-butyl 3-(3-((2-(diethylamino)-2-oxoethoxy)carbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.22 g, 0.38 mmol) was added 4M solution of HCl in dioxane (3 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain 2-(diethylamino)-2-oxoethyl 3-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-6a47c1e7a5014a46ba0f649737722879
Source noteuspto-grants-2014_04