Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2362899Generated: October 30, 2026

Hydrochloric Acid → HCID 66652084, compound

https://huagongshe.com/reaction/2362899

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 58046633HCID 58046633—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 66652084HCID 66652084—

Reaction Steps

To tert-butyl 3-(3-((2-(4-methylpiperazin-1-yl)-2-oxoethoxy)carbonyl)benzyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-8-carboxylate (0.16 g, 0.26 mmol) was added 4M solution of HCl in dioxane (3 mL). After stirring at room temperature for 2 hours, the reaction mixture was concentrated in vacuo to obtain 2-(4-methylpiperazin-1-yl)-2-oxoethyl 3-((4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decan-3-yl)methyl)benzoate as a hydrochloride salt.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691836B2
Source datasetuspto-grants-2014_04
ORD IDord-c0ecb1811f294880b5756257dc3706cd
Source noteuspto-grants-2014_04