HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl Ether → 1H-Purine-2,6-dione, 3,7-dihydro-3-(cyclohexylmethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl Ether | HCID 3283 | — |
| Reactant | Chloroform | HCID 6212 | — |
| Reactant | HCID 131714386 | HCID 131714386 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | 1H-Purine-2,6-dione, 3,7-dihydro-3-(cyclohexylmethyl)- | HCID 3058999 | — |
Reaction Steps
2 g of 5,6-diamino-1-cyclohexylmethyl-2,4-(1H,3H)-pyrimidine dione (XXII) was refluxed in 10 ml of formic acid for 1 h. 5 ml of chloroform was added and ether was then added slowly. The received crystals were filtered off. Yield 2.1 g (XXIII). The amide (XXIII) was refluxed in 15 ml of 2N NaOH for 1 hour and then neutralized with 5N HCl.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04644001 |
| Source dataset | uspto-grants-1987_02 |
| ORD ID | ord-fa4decf5ca3a4d4e919a7d6d18165f3b |
| Source note | uspto-grants-1987_02 |