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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2363104Generated: October 31, 2026

1-Methylidene-2,3-dihydro-1H-inden-4-ol → 1-Methylindan-4-ol

https://huagongshe.com/reaction/2363104

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylidene-2,3-dihydro-1H-inden-4-olHCID 45082820—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
SolventEthyl AcetateHCID 8857—
Product1-Methylindan-4-olHCID 8931093,579.297%

Reaction Steps

A mixture of 1-methylene-indan-4-ol (200 mg, 1.37 mmol) and 10% Pd/C (60 mg, 10% weight) in methanol (6 ml) was hydrogenated under 50 psi hydrogen atmosphere for 1 hour. The mixture was dissolved in EtOAc, filtered through a celite pad. The filtrate was concentrated under reduced pressure, and dried to give 1-methyl-indan-4-ol (190 g, 94%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691855B2
Source datasetuspto-grants-2014_04
ORD IDord-70ae8c466e8b4593ae071fdcf04c12c0
Source noteuspto-grants-2014_04