HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylidene-2,3-dihydro-1H-inden-4-ol → 1-Methylindan-4-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylidene-2,3-dihydro-1H-inden-4-ol | HCID 45082820 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-Methylindan-4-ol | HCID 89310 | 93,579.297% |
Reaction Steps
A mixture of 1-methylene-indan-4-ol (200 mg, 1.37 mmol) and 10% Pd/C (60 mg, 10% weight) in methanol (6 ml) was hydrogenated under 50 psi hydrogen atmosphere for 1 hour. The mixture was dissolved in EtOAc, filtered through a celite pad. The filtrate was concentrated under reduced pressure, and dried to give 1-methyl-indan-4-ol (190 g, 94%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-70ae8c466e8b4593ae071fdcf04c12c0 |
| Source note | uspto-grants-2014_04 |