HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 16110499, compound → HCID 67237736, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 16110499 | HCID 16110499 | — |
| Reactant | 2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide | HCID 67110887 | — |
| Product | HCID 67237736 | HCID 67237736 | 56.2% |
Reaction Steps
2-Chloro-oxazole-4-carboxylic acid [1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-amide (50 mg, 0.13 mmol) was reacted with 2-propyl-4-trifluoromethylphenol (37 mg, 0.18 mmol) to give the title compound (40 mg, 55%) after purification by flash chromatography on silica gel (gradient 12% to 100% EtOAc in n-hexane).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691855B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-b82efe7dc53c46e6a8cfe0157a70267b |
| Source note | uspto-grants-2014_04 |