Methane → HCID 13069250, compound

HRID 236339Notes

Reaction equation

HRID 236339 reaction equation
Cl.[CH2:2]([O:4][C:5]([C@@H:7]1[CH2:15][C:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[NH:8]1)=[O:6])[CH3:3].C>O>[CH2:2]([O:4][C:5]([C@@H:7]1[CH2:15][CH:14]2[CH:9]([CH2:10][CH2:11][CH2:12][CH2:13]2)[NH:8]1)=[O:6])[CH3:3]

Participants

4

Reactant 2

HCID 297MethaneHCID 22822759Ethyl indoline-2-carboxylate

Product 1

HCID 13069250HCID 13069250, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

The (2S)-2-ethoxycarbonylindoline hydrochloride obtained is hydrogenated in solution in 150 ml of water in the presence of 2 g of palladinised charcoal for 8 hours at 45° C. under 50 kg/cm2 pressure.

Sources & evidence

ORD record
ord-e649e0d48efd4376a86dd1d031b2ae10
Source dataset
uspto-grants-1987_02
Patent number
US04644008

Reaction notes

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