Methyl Anthranilate → HCID 178497644, compound

HRID 236398Notes

Reaction equation

HRID 236398 reaction equation
O.[NH2:2][C:3]1[NH:7][N:6]=[N:5][N:4]=1.[CH2:8](OC(OCC)OCC)C.[C:18]([O:27][CH3:28])(=[O:26])[C:19]1[C:20](=[CH:22][CH:23]=[CH:24][CH:25]=1)[NH2:21]>CC(O)C>[NH:4]1[C:3]([NH:2][CH:8]=[N:21][C:20]2[CH:22]=[CH:23][CH:24]=[CH:25][C:19]=2[C:18]([O:27][CH3:28])=[O:26])=[N:7][N:6]=[N:5]1

Participants

5

Reactant 3

HCID 8635Methyl AnthranilateHCID 31214Ethyl orthoformateHCID 178509300HCID 178509300, compound

Product 1

HCID 178497644HCID 178497644, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

A mixture of 12.1 g of 5-aminotetrazole monohydrate, 42 g of triethoxymethane, 21 g of methyl anthranilate and 50 ml of 2-propanol was stirred at room temperature under nitrogen for 2 days. The white solid which formed was separated by filtration, washed with 2-propanol and vacuum oven dried to give N1 -(1H-tetrazol-5-yl)-N2 -(2-carbomethoxyphenyl)formamidine which was identical with authentic material.

Workup

  1. customThe white solid which formed
  2. customwas separated by filtration
  3. washwashed with 2-propanol and vacuum oven
  4. customdried

Sources & evidence

ORD record
ord-aaebe5b6674a48b086a94cf340eac3a6
Source dataset
uspto-grants-1987_02
Patent number
US04644065

Reaction notes

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