Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66743399 | HCID 66743399 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 66743846 | HCID 66743846 | 97.3% |
Reaction Steps
A mixture of 7-bromo-1,2,2-trimethyl-6-(1H-pyrazol-4-yl)-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one (171 mg, 0.50 mmol), 1 M HCl (2.5 mL, 2.50 mmol) and MeOH (5 mL) was stirred at 50° C. for 1 h. The mixture was concentrated under reduced pressure to afford the title compound (182 mg, 97%) as a pale yellow solid. This material was used for the next reaction without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08691828B2 |
|---|
| Source dataset | uspto-grants-2014_04 |
|---|
| ORD ID | ord-a65204737e1747f78dcd68e78f3012da |
|---|
| Source note | uspto-grants-2014_04 |
|---|