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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2364026Generated: October 31, 2026

Hydrochloric Acid → HCID 66743846, compound

https://huagongshe.com/reaction/2364026

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66743399HCID 66743399—
SolventMethanolHCID 887—
ProductHCID 66743846HCID 6674384697.3%

Reaction Conditions

Temperature50 °C

Reaction Steps

A mixture of 7-bromo-1,2,2-trimethyl-6-(1H-pyrazol-4-yl)-2,3-dihydrothieno[3,2-d]pyrimidin-4(1H)-one (171 mg, 0.50 mmol), 1 M HCl (2.5 mL, 2.50 mmol) and MeOH (5 mL) was stirred at 50° C. for 1 h. The mixture was concentrated under reduced pressure to afford the title compound (182 mg, 97%) as a pale yellow solid. This material was used for the next reaction without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08691828B2
Source datasetuspto-grants-2014_04
ORD IDord-a65204737e1747f78dcd68e78f3012da
Source noteuspto-grants-2014_04