HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → HCID 69482769, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | Trifluoroacetic anhydride | HCID 9845 | — |
| Reactant | Methyl 3-amino-5-[(4-fluorophenyl)methyl]pyridine-2-carboxylate | HCID 58882991 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 69482769 | HCID 69482769 | — |
Reaction Steps
This compound was prepared from methyl 3-amino-5-[(4-fluorophenyl)methyl]-2-pyridinecarboxylate as described in Example 89, Steps 9-10 by reacting with trifluoroacetic anhydride, followed by alkylation with methyl iodide and subsequent deprotection upon heating in the presence of MeOH.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08691991B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-6019ec6ec64342209b6bd7f8f7238341 |
| Source note | uspto-grants-2014_04 |