Methanamine, N-methoxy-, hydrochloride (1:1) → HCID 86612796, compound

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Reaction Steps

This compound was prepared from [7-[(4-fluorophenyl)methyl]-4-hydroxy-3-({[2-(methyloxy)ethyl]amino}carbonyl)-2-oxo-1,5-naphthyridine-1(2H)-yl]acetic acid and N,O-dimethylhydroxylamine hydrochloride employing methods similar to those described in Example 558 and was obtained as a white solid: 1H NMR (d6-DMSO) δ 10.17 (1H, br t, J=5 Hz), 8.53 (1H, s), 7.82 (1H, s), 7.32 (2H, t, J˜8 Hz), 7.12 (2H, t, J˜9 Hz), 5.19 (2H, s), 4.12 (2H, s), 3.83 (3H, s), 3.53-3.48 (4H, m), 3.26 (3H, s), 3.12 (3H, s); AP+ MS: 473 (M+H+, 100).

Provenance & Evidence