Sodium borohydride → HCID 86649115, compound

Participants

Reaction Steps

To a solution of the product from Example 179A (10.0 g, 27.6 mmol) in EtOH (220 mL) was added sodium borohydride (2.190 g, 57.9 mmol) in several portions over 1 h. The resulting mixture was stirred at rt for 1 h, filtered through celite, and concentrated in vacuo. The residue was dissolved in EtOAc and washed by 1N aq. HCl. The organic layer was dried over Na2SO4, filtered and concentrated in vacuo to give the title compound (9.29 g, 92%)

Provenance & Evidence