Lactic Acid → 11006-76-1

HRID 2364923Notes

Reaction equation

HRID 2364923 reaction equation
[CH3:1][CH2:2][C@H:3]1[NH:35][C:33](=[O:34])[C@@H:32]([NH:36][C:37]([C:39]2[N:44]=[CH:43][CH:42]=[CH:41][C:40]=2[OH:45])=[O:38])[C@@H:31]([CH3:46])[O:30][C:28](=[O:29])[C@H:27]([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)[NH:26][C:24](=[O:25])[C@H:23]2[N:17]([CH2:18][CH2:19][C:20]([CH2:22]2)=[O:21])[C:15](=[O:16])[CH:14]([CH2:53][C:54]2[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=2)[N:13]([CH3:60])[C:11](=[O:12])[C@H:10]2[N:6]([CH2:7][CH2:8][CH2:9]2)[C:4]1=[O:5].C[C@H]1[C@@H](C(C)C)OC(=O)C2N(CCC=2)C(=O)C2=COC(=N2)CC(=O)C[C@H](O)C=C(C)C=CCNC(=O)C=C1.C(O)(=O)C(C)O.C1C(C2OC(CCC(O)=O)=CC=2)=CC=C(Cl)C=1.OC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.[OH-].[Na+]>>[CH3:1][CH2:2][CH:3]1[NH:35][C:33](=[O:34])[CH:32]([NH:36][C:37]([C:39]2[N:44]=[CH:43][CH:42]=[CH:41][C:40]=2[OH:45])=[O:38])[CH:31]([CH3:46])[O:30][C:28](=[O:29])[CH:27]([C:47]2[CH:52]=[CH:51][CH:50]=[CH:49][CH:48]=2)[NH:26][C:24](=[O:25])[CH:23]2[N:17]([CH2:18][CH2:19][C:20]([CH2:22]2)=[O:21])[C:15](=[O:16])[CH:14]([CH2:53][C:54]2[CH:59]=[CH:58][CH:57]=[CH:56][CH:55]=2)[N:13]([CH3:60])[C:11](=[O:12])[CH:10]2[N:6]([CH2:7][CH2:8][CH2:9]2)[C:4]1=[O:5]

Participants

6

Reactant 5

HCID 612Lactic AcidHCID 5780SorbitolHCID 14798Sodium HydroxideHCID 8081195-(4-Chlorophenyl)-2-furanpropionic acidHCID 71752965HCID 71752965, compound2×

Product 1

HCID 12273111006-76-1

Procedure

To determine the Lactrol® dose required to prevent lactic acid formation during hydrolysate fermentation, a portion of intentionally-contaminated seed culture F1067 at EFT=19.3 hr (from Example 1) was used as a seed culture to inoculate cob hydrolysate medium (FRF13; see General Methods) (adjusted to pH 5.8, +10 mM sorbitol) at 10 vol % (final volume) containing either 0 ppm (sample F1069) or 2 ppm (sample F1071) of Lactrol®, which was then fermented at 33° C. (reduced to 30° C. at EFT=21 hr) and pH 5.8 (adjusted with 4 N NaOH).

Workup

  1. customat EFT=19.3 hr (from Example 1)
  2. customwas then fermented at 33° C.

Sources & evidence

ORD record
ord-a33df8b4d5a24c3ba21aafdb33f1c7d0
Source dataset
uspto-grants-2014_04
Patent number
US08697426B2

Reaction notes

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