HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Piperidine-1-yl)-acetic acid-benzylester → Piperidin-1-yl-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Piperidine-1-yl)-acetic acid-benzylester | HCID 11379293 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Piperidin-1-yl-acetic acid | HCID 201097 | — |
Reaction Steps
10.4 g (44 mMol) (piperidine-1-yl)-acetic acid-benzylester 9 was stirred with 0.25 g Pd/C (5%) in 100 ml Methanol at RT. Under normal pressure, the reaction mixture was reduced (hydrated) with H2. After having removed the catalyst, the solution was evaporated and the residue was resuspended in EtOAc and filtered off.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697604B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-3c06d4dd3ff941a0b0af65238a7c5a8d |
| Source note | uspto-grants-2014_04 |