4-Aminotetrahydropyran → HCID 57329924, compound

Participants

Reaction Steps

As described for example 10 g, 4-methyl-2-[(E)-2-(3-methyl-5-pyridin-2-yl-3H-[1,2,3]triazol-4-yl)-vinyl]-thiazole-5-carboxylic acid (56 mg, 0.17 mmol), was converted, using 4-aminotetrahydropyran instead of isopropylamine, to the title compound (46 mg, 66%) which was obtained as a light yellow solid. MS: m/e=411.2 [M+H]+.

Provenance & Evidence