Hydrochloric Acid → HCID 86680947, compound

Participants

Reaction Steps

Tert-butyl 4-((4-((4-(3-bromopropoxy)benzyl)amino)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-yl)amino)benzoate (34 mg, 0.06 mmol) and 4 N HCl in dioxane (1 mL) were stirred for 8 hs then concentrated under vacuum to give 4-((4-((4-(3-bromopropoxy)benzyl)amino)-6-(2,2,2-trifluoroethoxy)pyrimidin-2-yl)amino)benzoic acid (31 mg, 0.06 mmol) which was carried to the next step without purification.

Provenance & Evidence