1,2,3,6-Tetrahydropyridine → HCID 20216140, compound

HRID 236550Notes

Reaction equation

HRID 236550 reaction equation
C([O:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][C:12]=1[O:13]C(=O)C)[CH:8]=O)(=O)C.[NH:17]1[CH2:22][CH:21]=[CH:20][CH2:19][CH2:18]1>CO>[OH:4][C:5]1[CH:6]=[C:7]([CH:10]=[CH:11][C:12]=1[OH:13])[CH2:8][N:17]1[CH2:18][CH:19]=[CH:20][CH2:21][CH2:22]1

Participants

4

Reactant 2

HCID 127501,2,3,6-TetrahydropyridineHCID 15174883,4-Diacetoxybenzaldehyde

Product 1

HCID 20216140HCID 20216140, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Using a similar procedure to that described in Example 7, but starting from 3,4-diacetoxybenzaldehyde (18.6 g.) and 1,2,3,6-tetrahydropyridine (13.9 g.) in methanol (150 ml.), there was obtained 1-(3,4-dihydroxybenzyl)-1,2,3,6-tetrahydropyridine as the free base (0.45 g.), m.p. >300° C.; microanalysis,

Sources & evidence

ORD record
ord-80cde4cb5b434134b99d802eb6ee0928
Source dataset
uspto-grants-1987_02
Patent number
US04645771

Reaction notes

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