HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isopropoxypropylamine → 3-(3-Isopropoxypropylsulfamoyl)benzoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isopropoxypropylamine | HCID 76194 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 3-(Chlorosulfonyl)-2-methylbenzoic acid | HCID 54395531 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(3-Isopropoxypropylsulfamoyl)benzoic acid | HCID 67086593 | — |
Reaction Steps
3-Isopropoxypropylamine (1.1 eq.) is dissolved in THF with stirring at room temperature. N,N-diisopropylethylamine (1 eq.) is added followed by methyl 3-(chlorosulfonyl)benzoic acid (1 eq.). The reaction mixture is stirred at room temperature for 2 hours before the solvent is evaporated in vacuo to yield the crude titled product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08697687B2 |
| Source dataset | uspto-grants-2014_04 |
| ORD ID | ord-32e74f3be3624f049b9eaa4912f5f53f |
| Source note | uspto-grants-2014_04 |