Hydrogen Bromide → 3-(3-piperidinyl)Phenol
Reaction equation
Br.C[O:3][C:4]1[CH:5]=[C:6]([CH:10]2[CH2:15][CH2:14][CH2:13][NH:12][CH2:11]2)[CH:7]=[CH:8][CH:9]=1>>[NH:12]1[CH2:13][CH2:14][CH2:15][CH:10]([C:6]2[CH:5]=[C:4]([OH:3])[CH:9]=[CH:8][CH:7]=2)[CH2:11]1Participants
3
Procedure
HBr can be prepared from 3-(3-methoxyphenyl)piperidine as described in J. Med. Chem., 24 (1981) 1475.
Sources & evidence
- ORD record
- ord-ee7e8154f03e4778885e1636af7d39a4
- Source dataset
- uspto-grants-2014_04
- Patent number
- US08697723B2
Reaction notes
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