Iodoethane → 1-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-ethyl-piperidine-3-carboxylic acid ethyl ester

HRID 2365984Notes

Reaction equation

HRID 2365984 reaction equation
[CH2:1]([O:3][C:4]([C:6]1([CH3:23])[CH2:11][CH2:10][CH2:9][N:8]([CH2:12][CH:13]2[O:18][C:17]3[CH:19]=[CH:20][CH:21]=[CH:22][C:16]=3[O:15][CH2:14]2)[CH2:7]1)=[O:5])[CH3:2].[CH2:24](I)C>>[CH2:1]([O:3][C:4]([C:6]1([CH2:23][CH3:24])[CH2:11][CH2:10][CH2:9][N:8]([CH2:12][CH:13]2[O:18][C:17]3[CH:19]=[CH:20][CH:21]=[CH:22][C:16]=3[O:15][CH2:14]2)[CH2:7]1)=[O:5])[CH3:2]

Participants

3

Reactant 2

HCID 6340IodoethaneHCID 251755001-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methylpiperidine-3-carboxylic acid ethyl ester

Product 1

HCID 251755011-(2,3-Dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-ethyl-piperidine-3-carboxylic acid ethyl ester

Procedure

Prepared according to the procedure described above for 1-(2,3-dihydrobenzo[1,4]dioxin-2-ylmethyl)-3-methylpiperidine-3-carboxylic acid ethyl ester except that ethyl iodide was used instead of methyl iodide.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-c99d409f49c94b448e4e189c57cff88a
Source dataset
uspto-grants-2014_04
Patent number
US08697723B2

Reaction notes

Loading…