反应详情

0.1N Hydrochloric acid (3.7 mL) was added to Compound 22 (117 mg), and purified water (30 mL), acetonitrile (30 mL), and chloroform (5 mL) were added to the mixture, to thereby dissolve the mixture. The solution was stirred at room temperature for 1 hour, and the solvent was evaporated to dryness. The residue was suspended in hexane-ethyl acetate, and the solvent was evaporated to dryness, followed by thoroughly drying, to thereby yield the target product (yield: 124 mg, 96%).

1. custompurified water (30 mL), acetonitrile (30 mL), and chloroform (5 mL)
2. additionwere added to the mixture
3. dissolutionto thereby dissolve the mixture
4. customthe solvent was evaporated to dryness
5. customthe solvent was evaporated to dryness
6. customby thoroughly drying