3-Pyridinecarboxaldehyde → HCID 11965500, compound

HRID 2366389Notes

Reaction equation

HRID 2366389 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]=O)[CH:2]=1.[CH3:9][O:10][C:11]1[CH:12]=[C:13]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH2:14][C:15]#[N:16]>>[CH3:9][O:10][C:11]1[CH:12]=[C:13](/[C:14](=[CH:7]/[C:3]2[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=2)/[C:15]#[N:16])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

Participants

3

Reactant 2

HCID 103713-PyridinecarboxaldehydeHCID 667273,4-Dimethoxybenzeneacetonitrile

Product 1

HCID 11965500HCID 11965500, compoundYield 90%

Procedure

3-Pyridinecarboxaldehyde (2.14 g) was condensed with 3,4-dimethoxybenzyl cyanide (3.54 g) through Method A (production step 2), to thereby yield the target product (yield: 4.79 g, 90%).

Sources & evidence

ORD record
ord-db3f8b33b73349a7b350852c25ccf9a4
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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