Veratraldehyde → 138989-48-7

HRID 2366398Notes

Reaction equation

HRID 2366398 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][C:8]#[N:9].[CH3:10][O:11][C:12]1[CH:13]=[C:14]([CH:17]=[CH:18][C:19]=1[O:20][CH3:21])[CH:15]=O>>[CH3:10][O:11][C:12]1[CH:13]=[C:14](/[CH:15]=[C:7](/[C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)\[C:8]#[N:9])[CH:17]=[CH:18][C:19]=1[O:20][CH3:21]

Participants

3

Reactant 2

HCID 8419VeratraldehydeHCID 75959Pyridine-2-acetonitrile

Product 1

HCID 5467797138989-48-7Yield 77.4%

Procedure

2-Pyridineacetonitrile (1.18 g) was condensed with 3,4-dimethoxybenzaldehyde (1.66 g) through Method B (production step 2), to thereby yield the target product (yield: 2.06 g, 77%).

Sources & evidence

ORD record
ord-40122a29d6904270936d0dd12bfa1a43
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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