Pyridine-2-acetonitrile → HCID 11964640, compound

HRID 2366430Notes

Reaction equation

HRID 2366430 reaction equation
[N:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH:11]=O)=[CH:3][CH:2]=1.[N:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[CH2:19][C:20]#[N:21]>>[N:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1/[C:19](=[CH:11]/[C:4]1[C:5]2[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=2)[N:1]=[CH:2][CH:3]=1)/[C:20]#[N:21]

Participants

3

Reactant 2

HCID 75959Pyridine-2-acetonitrileHCID 780724-Quinolinecarboxaldehyde

Product 1

HCID 11964640HCID 11964640, compoundYield 54%

Procedure

4-Quinolinecarboxaldehyde (157 mg) was condensed with 2-pyridineacetonitrile (118 mg) through Method B (production step 3), to thereby yield the target product (yield: 138 mg, 54%).

Sources & evidence

ORD record
ord-d6188d0028e24221a2ce98734ca50749
Source dataset
uspto-grants-2014_04
Patent number
US08697742B2

Reaction notes

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