Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Cyanamide | HCID 9864 | — |
| Reactant | 1-(4-(3-Aminophenyl)thiazol-2-yl)guanidine | HCID 178512611 | — |
| Product | HCID 178512249 | HCID 178512249 | — |
Reaction Steps
A mixture of 23.3 gm of 2-guanidino-4-(3-amino-phenyl)-thiazole, 18.5 gm of ethyl ortoformate and 4.2 gm of cyanamide was heated at 120° C. for 15 minutes, cooled to room temperature, treated with ethanol and filtered, yielding 23 gm of the title compound, m.p. 214°-216° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04645841 |
|---|
| Source dataset | uspto-grants-1987_02 |
|---|
| ORD ID | ord-85aef446293f4b9187ec92eac1323eec |
|---|
| Source note | uspto-grants-1987_02 |
|---|
