Methylamine → HCID 178484909, compound

HRID 236654Notes

Reaction equation

HRID 236654 reaction equation
[C:1]([NH:3][CH:4]=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]2[N:13]=[C:14]([NH:17][C:18]([NH2:20])=[NH:19])[S:15][CH:16]=2)[CH:7]=1)#N.CN>O>[CH3:1][NH:3][CH:4]=[N:5][C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]2[N:13]=[C:14]([NH:17][C:18]([NH2:20])=[NH:19])[S:15][CH:16]=2)[CH:7]=1

Participants

4

Reactant 2

HCID 6329MethylamineHCID 178512249HCID 178512249, compound

Product 1

HCID 178484909HCID 178484909, compoundYield 69.2%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

4 gm of N-cyano-N'-[3-(2-guanidino-4-thiazolyl)-phenyl]-formamidine were added all at once to 40 ml of 35% methylamine in water (40 ml). A few minutes later, the reaction product separated out of the solution. This solid was filtered, washed with water and dried, yielding 2.66 gm of the title compound.

Workup

  1. customA few minutes later, the reaction product separated out of the solution
  2. filtrationThis solid was filtered
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-a0cfc0afe5624b5896703a78fe368bea
Source dataset
uspto-grants-1987_02
Patent number
US04645841

Reaction notes

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